![youtube vitamin d video youtube vitamin d video](https://guideabouthealth.com/wp-content/uploads/2021/11/pill-1024x678.jpg)
![youtube vitamin d video youtube vitamin d video](https://www.vitamin-d-fakten.de/wp-content/uploads/2020/09/104446389_m.jpg)
Ongoing observational studies are evaluating the role of vitamin D in preventing and treating COVID-19. The rationale for using vitamin D is based largely on immunomodulatory effects that could potentially protect against COVID-19 infection or decrease the severity of illness. 7,8 High levels of vitamin D may cause hypercalcemia and nephrocalcinosis. 6 However, in two double-blind, placebo-controlled, randomized clinical trials, administering high doses of vitamin D to critically ill patients with vitamin D deficiency (but not COVID-19) did not reduce the length of the hospital stay or the mortality rate when compared to placebo. 5 In a meta-analysis of randomized clinical trials, vitamin D supplementation was shown to protect against acute respiratory tract infection.
![youtube vitamin d video youtube vitamin d video](https://i.ytimg.com/vi/16YcJ8ZxsPo/maxresdefault.jpg)
Vitamin D supplements may increase the levels of T regulatory cells in healthy individuals and patients with autoimmune diseases vitamin D supplements may also increase T regulatory cell activity. In observational studies, low vitamin D levels have been associated with an increased risk of community-acquired pneumonia in older adults 3 and children. 2 Vitamin D deficiency is also more common in older patients and patients with obesity and hypertension these factors have been associated with worse outcomes in patients with COVID-19. These groups are also overrepresented among cases of COVID-19 in the United States. Vitamin D deficiency (defined as a serum concentration of 25-hydroxyvitamin D ≤20 ng/mL) is common in the United States, particularly among persons of Hispanic ethnicity and Black race. Because the vitamin D receptor is expressed on immune cells such as B cells, T cells, and antigen-presenting cells, and because these cells can synthesize the active vitamin D metabolite, vitamin D also has the potential to modulate innate and adaptive immune responses. Vitamin D is critical for bone and mineral metabolism.